Peripheral artery disease (PAD) often affects the femoral artery, causing pain, cramping and other problems in your legs. The artery is a common access point for minimally invasive, catheter-based procedures because of its large diameter. It’s in your upper thigh, right near your groin. The femoral artery is the major blood vessel supplying blood to your legs. This may happen if the tissues don’t receive blood or oxygen for a prolonged period of time. In extreme situations, a blocked artery in your leg can lead to amputation (removal) of your toes, foot or leg. Long-term narrowing or total blockage of the femoral artery can cause claudication, fatigue and painful cramping in the calf muscles when walking.
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